The use of oral probiotics as an adjunct in the treatment of acne vulgaris:

a double-blind randomized clinical trial

Abstract

Objective.To analyze the effectiveness of oral probiotics in the treatment of acne vulgaris. Methods.This is a controlled, double-blind, randomized clinical trial, with a duration of three months and the participation of 20 patients with acne vulgaris, the experimental group received the oral probiotic and adapalene 1 mg topical cream, while the control group received the placebo probiotic and the same topical cream. Results and Discussion.When analyzing the degree of improvement in the clinical appearance of acne, in the control group there was an initial average of 2.30 (±0.82) and after treatment, 1.70 (±1.16) of final average, while the experimental group presented an initial average of degree 2.80 (±1.03) and passed to an average of 1.60 (±0.70), this decrease in the average indicates a reduction in the amount and acne severity, more expressive in the experiment group. Conclusion.Significant improvement in acne reduction and quality of life was noted with the use of oral probiotics.

DESCRIPTORS: Acne; Dermatology; Randomized Clinical Trial.